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Azathioprine is classified as immunosuppressant treatment. This prescription is prescribed to suppress immune system in patients who had kidney changes. Though its exact mechanism of action in a rheumatic arthritis is not known, its effect in suppression of immune system, apparently, reduces activity of this illness.
The tablet: 50 mg; It can be given also is intravenouslied.
Azathioprine is prescribed to forbid the immune answer which causes an abnormality of kidney changes. Azathioprine also it is prescribed for treatment of a serious, active rheumatic arthritis. It - considered "the second line ", or "slowly - working "the prescription also is usually kept for rheumatic patients of an arthritis who do not answer other first line or treatments of the second line.
Azathioprine can cause increase in risk of a cancer when it is prescribed long-term. This specific risk increases in patients with a previous history of treatment with others powerful immunosuppressant, such as Cytoxan, Leukeran, and Alkeran. . Azathioprine can harm to abundance, reducing sperm counts in men. As toxicity Azathioprine increases, when taken with treatment of a gout Allopurinol (Zyloprim), its dose is reduced with simultaneous use. Strictly low white blood, counts can take place when taken with another drugs which can mention a bone brain or with a class of the INHIBITOR of the ACE drugs, was in the habit to treat the lifted blood pressure, such as Accupril and Vasotec. Safety and efficiency for use in children have not been established.
The most common serious side effects Azathioprine involve elements of blood and gastrointestinal system. Azathioprine can cause serious downturn of a white blood cell count, the termination by the increased risk of infections. It can reserve, when the dose is reduced or temporarily stopped. Azathioprine can cause a nausea, vomiting, and loss of appetite which can solve when the dose is reduced or divided within day. Azathioprine can cause also toxicity of a liver (in less than 1 % of rheumatic patients of arthritis). All patients taking Azathioprine demand correct test of blood for blood counts and tests of function of a liver for the control. Other sides effects with which collide less frequently include weariness, loss of hair, pains of a joint, and the diarrhea.
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